Hexagon Bio’s mission to identify medicines encoded in the global metagenome, and bring them to patients. While nature’s molecules have proven to be a rich source of potent medicines, their translation has been laborious and hindered by the lack of mechanistic understanding of the intended target. Hexagon Bio’s interdisciplinary platform uses data science, genomics, synthetic biology and automation to discover evolutionarily refined molecules and their protein targets directly from fungal genomes.